This Mental Health Day, we look at the lifecycle through the lens of mental health

By:  Talking Nutrition Editors

 

Summary

  • October 10th marks World Mental Health Day, introduced by the World Health Organization (WHO) to raise awareness of mental health issues and mobilize efforts in support of mental health globally.
  • The theme of this World Mental Health Day is ‘mental health is a universal right’, with the aim of driving actions that promote and protect mental health as an essential freedom.
  • Read on to learn more about how nutrition, as one important modifiable factor, can support mental wellness at all stages of the lifecycle and discover cutting-edge nutritional solutions that aim to improve outcomes for people worldwide.

World Mental Health Day – celebrated on the 10th of October each year – aims to raise awareness of psychiatric conditions and to mobilize efforts in support of mental wellness globally. As a purpose-led company, dsm-firmenich is passionate about advancing mental health and wellbeing to help create a brighter tomorrow. This World Mental Health Day, we explore how cutting edge-nutritional solutions can support optimal mental wellness outcomes for people worldwide at all stages of the lifecycle.

Mental health across the lifecycle

As many as one in eight people globally live with a mental health condition that can negatively impact their physical health, relationships, livelihoods and wellbeing. Adolescents and young people are increasingly affected, with serious conditions such as major depressive disorder (MDD), bipolar disorder, anxiety disorders and psychotic disorders – including schizophrenia – frequently diagnosed during adolescence, whereas attention deficit hyperactivity disorder (ADHD) is typically diagnosed even earlier, with most receiving a diagnosis before 7 years old. As mental disorder in adolescence increase the risk of later adult disorder, interventions in early life have the potential to be highly impactful by preventing present and long-term impairment.

The idea of ‘prevention’ is relatively new to mental health care and remains somewhat controversial. However, emerging research indicates that nutritional interventions with essential minerals, vitamins, and specific fatty acids, such as omega 3s, may mitigate related risk factors for mental illness and promote optimal brain health, although additional research is required.

Tackling mental health challenges as a mom

Bringing a new life into the world is one of the most momentous and joyous experiences imaginable. However, it also comes with significant challenges as new parents strive to meet the little one’s needs. A sudden lack of sleep and loss of ‘me time’ can exacerbate feelings of stress and fatigue for all new mothers, whether they are lactating or otherwise.7 Research has shown that balancing fatigue with post-natal recovery in the postpartum period can cause mood fluctuations, anxiety and stress.

In pregnant women experiencing depression or in those who have recently given birth and are dealing with depressive symptoms, lower levels of EPA and DHA have also been observed. This omega-3 deficiency may potentially link to ongoing low-level inflammation and underlying physiological processes associated with depressive disorders. Multiple studies have demonstrated that supplementing with omega-3 long-chain polyunsaturated fatty acids (LCPUFAs), particularly those high in EPA, can have a positive impact on the mood of adults and help alleviate symptoms of depression, including those commonly experienced during perinatal depression.

Not only can omega-3 supplementation potentially support mothers with mood volatility typical of the postpartum period, it can also have a positive impact on a baby’s long-term health. Nutrition during the first 1,000 days of life is critical for human development and lays the foundation for a healthy future. During this period, omega-3 and omega-6 LCPUFAs – namely DHA and ARA – support neurocognitive development, which is implicated with mental health and life quality in later life.

Self-care: a proactive approach to mental wellbeing

As many as 63% of adults worldwide are concerned about their mental and emotional health, considering it their second biggest health priority after energy. Adults are increasingly taking a proactive and preventative approach to their mental wellbeing, aiming to improve their quality of life through self-care endeavors such as an improved diet and supplement regimes.

Against this backdrop of rising awareness in self-care, whether products are “natural” or “clean” remains a major driver of consumer adoption. Happily, there are many diverse natural ingredients that are available for innovation in the cognitive health and mental wellness space. As well as omega-3s, cannabidiol (CBD), magnesium, ashwagandha, B vitamins and ginkgo are gaining relevance as neuroprotectives. While CBD, ashwagandha and magnesium are linked to stress management, anxiety and sleep, B vitamins can play a role in supporting energy and general health. dsm-firmenich is bringing progress to life in the mental health arena by championing nootropic innovation with natural ingredients to support healthy sleep, mood and stress reduction.

Active minds: changing the conversation about mental health in the elderly

As the global population ages, declining brain health is a major issue, with memory, learning and other cognitive functions all negatively impacted by the ageing process. Approximately 15% of adults aged 60 and over suffer from a mental disorder. Poor cognition can result from inadequate nutrition, and at the same time affect a person's nutritional status, as well as their mobility, independence and quality of life. However, there are ways to support mental health in later life; among several modifiable factors - such as physical activity and social interactions - also through nutritional care . While there is currently no cure for dementia, research suggests omega-3 fatty acids, lutein, B-vitamins and vitamins D and E can support cognitive function and reduce the risk of developing the disorder. Let’s take a closer look at omega-3 fatty acids. A recent study suggests that omega-3 fatty acids, especially DHA, may be effective at mitigating the most damaging effects of aging on the brain. As the brain ages, myelin sheaths – the neuroprotective insulation that forms around nerve cells to facilitate rapid communication as well as normal motor and sensory function and cognition – degenerate. Consequently, the elderly experience a decline in mental and physical abilities. But new research suggests that omega-3s may support myelin retention in the aging brain, creating new supplementation opportunities for nutrition brands. We’re committed to developing solutions that support the health of the aging population, and are the only provider of  life’s®OMEGA, a plant-based omega-3 that delivers the benefits of EPA and DHA in a single, quality source.

dsm-firmenich: committed to advancing mental health and well-being worldwide

dsm-firmenich understands that nutritional solutions can have a positive impact on mental wellness at all stages of a person’s life. We are committed to bringing progress to life in the mental health space by championing innovation in novel health benefit solutions, from advancing research into compounds to developing unique ingredients supported by diverse formats to empower minds worldwide, young and old.

But supporting mental health across the globe takes more than ingredients. It takes a partner. We’re inspired to create a brighter future tomorrow via our portfolio of high-quality products, customized solutions and expert services that help you bring life-enhancing products to market faster.

Discover how to co-create exciting nutritional health solutions for mental wellbeing at all stages of life.

References

  1. World Health Organization. World Mental Health Day 2023. 2023 [Accessed 03/10/2023] World Mental Health Day 2023 (who.int).
  2. G. Xu et al., ‘Twenty-year trends in diagnosed attention-deficit/hyperactivity disorder among US children and adolescents, 1997-2016.’ JAMA Network Open. 2018;1:e181471.
  3. R.C. Kessler et al., ‘Twelve-month and lifetime prevalence and lifetime morbid risk of anxiety and mood disorders in the United States.’ Int J Methods Psychiatr Res. 2012;21:169-184.
  4. Eyre, Olga et al. Common adolescent mental disorders: transition to adulthood. The Lancet, Volume 383, Issue 9926, 1366 – 1368.
  5. C. Lassale et al., ‘Healthy dietary indices and risk of depressive outcomes: a systematic review and meta-analysis of observational studies.’ Mol Psychiatry. 2018.
  6. G. Grosso et al., Dietary n-3 PUFA, fish consumption and depression: A systematic review and meta-analysis of observational studies. J Affect Disord. 2016;205:269-281.
  7. Okun ML. Sleep and postpartum depression. Curr Opin Psychiatry. 2015 Nov;28(6):490-6.
  8. Mocking RJT, Steijn K, Roos C, Assies J, Bergink V, Ruhé HG, Schene AH. Omega-3 Fatty Acid Supplementation for Perinatal Depression: A Meta-Analysis. J Clin Psychiatry. 2020 Sep 1;81(5):19r13106.
  9. Guu TW, Mischoulon D, Sarris J, Hibbeln J, McNamara RK, Hamazaki K, Freeman MP, Maes M, Matsuoka YJ, Belmaker RH, Jacka F, Pariante C, Berk M, Marx W, Su KP. International Society for Nutritional Psychiatry Research Practice Guidelines for Omega-3 Fatty Acids in the Treatment of Major Depressive Disorder. Psychother Psychosom. 2019;88(5):263-273.
  10. Ravindran AV, Balneaves LG, Faulkner G, Ortiz A, McIntosh D, Morehouse RL, Ravindran L, Yatham LN, Kennedy SH, Lam RW, MacQueen GM, Milev RV, Parikh SV; CANMAT Depression Work Group. Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder: Section 5. Complementary and Alternative Medicine Treatments. Can J Psychiatry. 2016 Sep;61(9):576-87. doi: 10.1177/0706743716660290. Epub 2016 Aug 2.
  11.  Suradom C, Suttajit S, Oon-Arom A, Maneeton B, Srisurapanont M. Omega-3 polyunsaturated fatty acid (n-3 PUFA) supplementation for prevention and treatment of perinatal depression: a systematic review and meta-analysis of randomized-controlled trials. Nord J Psychiatry. 2021 May;75(4):239-246.
  12. Chang JP et al. Polyunsaturated fatty acids and inflammatory markers in major depressive episodes during pregnancy. Progress in Neuropsychopharmacology & Biological Psychiatry, vol. 80 (part C), pg. 273-278, 2018.
  13. Lin P et al. Polyunsaturated fatty acids in perinatal depression: a systematic review and meta-analysis. Biological Psychiatry, vol. 82, no. 8, pg. 560-569, 2017.
  14. Lassale C et al. Healthy dietary indices and risk of depressive outcomes: a systematic review and meta-analysis of observational studies. Mol Psychiatry, vol. 24, no. 7, pg. 965-986, 2018.
  15. Grosso G et al., Dietary n-3 PUFA, fish consumption and depression: A systematic review and meta-analysis of observational studies. J Affect Disord., vol. 205, pg. 269-281, 2016.
  16. Lepping RJ et al. Long-chain polyunsaturated fatty acid supplementation in the first year of life affects brain function, structure, and metabolism at age nine years. Developmental Psychobiology, vol. 61, no. 1, pg. 5-16, 2019.
  17. Colombo J et al. Docosahexaenoic acid (DHA) and arachidonic acid (ARA) balance in developmental outcomes. Prostaglandins Leukot Essent Fatty Acids, vol 121, pg. 52-56, 2017.
  18. Cohen Kadosh K, Muhardi L, Parikh P, Basso M, Jan Mohamed HJ, Prawitasari T, Samuel F, Ma G, Geurts JM. Nutritional Support of Neurodevelopment and Cognitive Function in Infants and Young Children-An Update and Novel Insights. Nutrients. 2021 Jan 10;13(1):199.
  19. DSM Global Consumer Health Survey, 2023.
  20. Nielson Holdings Global Consumer Health and Wellness Report 2021.
  21. McKinsey & Company. Wellness worldwide: Consumer insights from four countries. April 8, 2021. [Accessed 03/10/2023] Health and wellness worldwide: Consumer insights from four countries | McKinsey.
  22. dsm-firmenich proprietary data (upcoming Nootropics report 2023).
  23. Brain health, World Health Organization. Available at: Brain health (who.int)
  24. van de Rest et al. Effect of fish oil on cognitive performance in older subjects: a randomized, controlled trial. Neurology, vol. 71, no. 6, pg. 430–438, 2008.
  25. Janssen et al. Long-chain polyunsaturated fatty acids (LCPUFA) from genesis to senescence: the
  26. Influence of LCPUFA on neural development, aging and neurodegeneration. Prog Lipid Res., vol. 53, pg. 1–17, 2014.
  27. Johnson et al. Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women. Nutr Neurosci., vol. 11, no. 2, pg. 75–83, 2008.
  28. Douaud et al. Preventing Alzheimer’s diseaserelated gray matter atrophy by b-vitamin treatment. PNAS, vol. 110, no. 23, pg. 9523–9528, 2013
  29. Bowman et al. Nutrient biomarker patterns, cognitive function and MRI measures of brain aging.
  30. Neurology, vol. 78, no. 4, pg. 241–249, 2012
  31. Walker et al. Oral folic acid and vitamin B-12 supplementation to prevent cognitive decline in community-dwelling older adults with depressive symptoms – the Beyond Aging Project: a randomized controlled trial. Am J Clin Nutr., vol. 95, no. 1, pg. 194–203, 2012
  32. Smith et al. Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild
  33. Cognitive impairment: a randomized controlled trial. PLoS One, vol. 5, no. 9, e12244, 2010.
  34. Landel et al. Vitamin D, cognition and Alzheimer’s Disease: the therapeutic benefit is in the D-tails.
  35.  J Alzheimer’s Dis., vol. 53, no. 2, pg. 419–444, 2016.
  36. Lynn MU et al. Vitamin E and neurodegeneration. Neurol Dis., vol. 84, pg. 78–83, 2015.
  37. Sengottuvel V, Hota M, Oh J, Galam DL, Wong BH, Wenk MR, Ghosh S, Torta F, Silver DL. Deficiency in the omega-3 lysolipid transporter Mfsd2a leads to aberrant oligodendrocyte lineage development and hypomyelination. J Clin Invest. 2023 Apr 27:e164118.

Published on

06 October 2023

Share

5 min read

Sign up for our newsletter

   Stay up-to-date on the latest science, events and market trends

We are social

Follow us on your favorite social networks.

Follow Us:

Quick Links

Premix Solutions

Customized blends of desired functional ingredients in one single, efficient, homogenous premix.

Health Benefits & Solutions

Solutions to address consumers' health and lifestyle needs.

Market-ready Solutions

Streamline your product development process and get to market faster.

dsm-firmenich.com

We're innovators in nutrition, health, and beauty. And we bring progress to life!

Talking Nutrition

Explore new science, consumer insights, industry events and more.

Customer Portal

Request samples, place orders and view product documentation.