Boosting milk yield by promoting health? YES please!

In brief:

  • Vitamin D plays a very important role in improving calcium and phosphorous metabolism as well as immunity
  • Optimal vitamin D status results in reduced inflammation and increased milk yield
  • Common sources of vitamin D like the sun, or supplemental vitamin D3, are not enough to support nutritional recommendations for high milk yield cows – so what’s the alternative for producers?

Vitamin D: Elevating the health status

In dairy farming, the wellbeing of each cow holds the key to unlocking the full potential of the herd. Behind every high yielding dairy cow lies a delicate balance between health and productivity. There are many factors that impact the cow’s physical well-being, shaping not only their individual performance but also the overall efficiency and profitability of the operation.

Vitamin D’s impact in the health of ruminants has gained relevance in the recent years, as well as in any other species. For ruminants, two clear areas of the impact of vitamin D in health are:

Optimal Status: Vitamin D and Milk Yield

Both major known areas of impact of vitamin D – calcium and phosphorous metabolism and immunity - play a very important role on the health of the animals. Consequently, the energy balance results in the greater milk production capacity.

One of the main reasons health is critical for optimal milk production is the expense associated with activating the immune system of animals. Inflammation is a natural process, defending against pathogens that may impact health negatively. However, inflammation that is excessive in magnitude and length of time does result in harm to the animal (Brewer et al., 2020).

  • Root cause of diseases: Pathological inflammation can be harmful because it may act as the starting point of several diseases, as suggested by Horst et al. (2021). Inflammation commonly can result in failures such as fatty liver, ketosis, hypocalcemia, impaired reproduction and others. Any one of these diseases will limit the wellbeing of the cow and will limit her capacity to express her productive potential.
Adapted from Horst et al. (2021)
  • Energy expenditure: pathological inflammation also can result simply on a high energy expenditure for the animal. According to Kvidera et al. (2016), a dairy cow and a steer spend 0.64 and1.0g glucose/ kg BW0.75/h. An experiment using an LPS-euglycemic clamp to quantify the energetic cost of an activated immune system indicated a loss of approximately 1 kg of glucose used by the immune system, during a 12-hour period in lactating dairy cows. Therefore, the stronger and the more prolonged the immune reaction, the more likely this will result on reduced energy availability, resulting in milk losses.

Common Health Factors: Is Lack of Vitamin D limiting the milk yield?

Vitamin D3 or Sun exposure are not enough

The two common ways of absorbing vitamin D are via the sun, or through feed, commonly as vitamin D3. However, there is a major limitation as to how much can a cow transform into 25-OH vitamin D3, which is later converted in the kidney into 1,25OHD3, the active form (Figure 1).

Figure 1. Vitamin D natural pathway and with Hy-D, bypassing the liver’s bottleneck.

Supplementing with products such as Hy-D® supports the cow in the metabolism of vitamin D3. It bypasses the critical first step of hydroxylation in the liver and reaches the blood stream quickly and efficiently. The key advantage of Hy-D® as a vitamin D source is that it bypasses the liver’s bottleneck and ensures the animal can reach blood levels associated with optimal immune function (Nelson et al., 2010).

Conventional vitamin D3 vs Hy-D®

The table below summarizes various dairy trials in dairy cows that compared conventional vitamin D3 supplementation with the use of Hy-D®. Hy-D® has been tested in different forms of application during dry period (green), during milking period (purple) and one trial covered both stages (blue).

Most of the trials demonstrated significant positive impacts in health status for the animals (column “health outcomes”). The biggest impact of the use of Hy-D® on those trials was the enhanced health and resilience in all bovine categories (e.g. calves, heifers, beef) although the trials in the table above were all on dairy cows.

Consistently, Hy-D® led to higher milk yield, during both early and late lactation. The range of increase on ECM yield when comparing with vitamin D3 as a control was of 0.9 – 3.9 kg.

What’s Next?

With Hy-D®’s new registration in the EU, farmers and nutritionists can consistently support improvement in milk yield, both during early and late lactation, at the same time as promoting a better health status, altogether enhancing the profitability of the farming system.

References

  • Bradford, B.J., Yuan, K., Farney, J.K., Mamedova, L.K. and Carpenter, A.J., 2015. Invited review: Inflammation during the transition to lactation: New adventures with an old flame. Journal of dairy science, 98(10), pp.6631-6650.
  • Brewer, A., Cormican, P., Lim, J.J., Chapwanya, A., O’Farrelly, C. and Meade, K.G., 2020. Qualitative and quantitative differences in endometrial inflammatory gene expression precede the development of bovine uterine disease. Scientific reports, 10(1), p.18275.
  • Holub, G.A., Chapman, J.D., Zanzalari, K.P., Gott, P.N., Craig, B.M. and Dann, H.M., 2023. PSVII-27 Effect of Pre-And Postpartum Supplementation of 25-Hydroxyvitamin D 3 on Lactational Performance of Holstein Cows. Journal of Animal Science, 101(Supplement_3), pp.632-633.
  • Horst, E.A., Kvidera, S.K. and Baumgard, L.H., 2021. Invited review: The influence of immune activation on transition cow health and performance—A critical evaluation of traditional dogmas. Journal of Dairy Science, 104(8), pp.8380-8410.
  • Kvidera, S.K., Horst, E.A., Abuajamieh, M., Mayorga, E.J., Fernandez, M.S. and Baumgard, L.H., 2017. Glucose requirements of an activated immune system in lactating Holstein cows. Journal of dairy science, 100(3), pp.2360-2374.
  • Martinez, N., Sinedino, L.D.P., Bisinotto, R.S., Ribeiro, E.S., Gomes, G.C., Lima, F.S., Greco, L.F., Risco, C.A., Galvão, K.N., Taylor-Rodriguez, D. and Driver, J.P., 2014. Effect of induced subclinical hypocalcemia on physiological responses and neutrophil function in dairy cows. Journal of dairy science, 97(2), pp.874-887.
  • Martinez, N., Rodney, R.M., Block, E., Hernandez, L.L., Nelson, C.D., Lean, I.J. and Santos, J.E.P., 2018. Effects of prepartum dietary cation-anion difference and source of vitamin D in dairy cows: Lactation performance and energy metabolism. Journal of Dairy Science, 101(3), pp.2544-2562.
  • Nelson, C.D., Reinhardt, T.A., Thacker, T.C., Beitz, D.C. and Lippolis, J.D., 2010. Modulation of the bovine innate immune response by production of 1α, 25-dihydroxyvitamin D3 in bovine monocytes. Journal of dairy science, 93(3), pp.1041-1049.
  • Ribeiro, I. C. O., Silva, R. B., Resende, L. N., Pereira , R. A. N., Cortinhas, C. S., Acedo, T. S., Lacreta Junior, A. C. C. and Pereira, M. N., 2019. Calcidiol increased milk yield and reduced somatic cell count of late-lactation dairy cows. Journal of Dairy Science, 102(1) (Abstr.).
  • Rodney, R.M., Celi, P., McGrath, J.J., Golder, H.M., Anderson, S.T., McNeill, D.M., Fraser, D.R. and Lean, I.J., 2018. Metabolic and production responses to calcidiol treatment in mid-lactation dairy cows. Animal production science, 59(3), pp.449-460.
  • Silva, A.S., Cortinhas, C.S., Acedo, T.S., Morenz, M.J.F., Lopes, F.C.F., Arrigoni, M.B., Ferreira, M.H., Jaguaribe, T.L., Ferreira, L.D., Gouvêa, V.N. and Pereira, L.G.R., 2022. Effects of feeding 25-hydroxyvitamin D3 with an acidogenic diet during the prepartum period in dairy cows: Mineral metabolism, energy balance, and lactation performance of Holstein dairy cows. Journal of Dairy Science, 105(7), pp.5796-5812.
  • Xu, H., Zhang, Q., Wang, L., Zhang, C., Li, Y. and Zhang, Y., 2021. Effects of 25-hydroxyvitamin d3 and oral calcium bolus on lactation performance, ca homeostasis, and health of multiparous dairy cows. Animals, 11(6), p.1576.
  • Xu, H.J., Jiang, X., Zhang, C.R., Ma, G.M., Wang, L.H., Zhang, Q.Y. and Zhang, Y.G., 2021. Effects of dietary 25-hydroxyvitamin D3 on the lactation performance, blood metabolites, antioxidant and immune function in dairy cows. Livestock Science, 248, p.104497.

Published on

25 July 2024

Tags

  • Ruminants
  • Dairy
  • Vitamins
  • Vitamin D3
  • Hy-D

About the Author

Ignacio Artavia - Global Marketing Manager for Ruminants, Animal Nutrition and Health at dsm-firmenich

Ignacio holds a bachelor's in Agriculture Sciences and a master's in Sustainable Animal Nutrition and Feeding. He is the Global Marketing Manager for Ruminants at dsm-firmenich, and has supported farmers, nutritionists, and health experts on promoting productive performance through health protection and efficient use of resources.

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